Author Archives: Byung-Jun Yoon

About Byung-Jun Yoon

I am an Associate Professor at Texas A&M University, Department of Electrical & Computer Engineering, and a Scientist at Brookhaven National Laboratory, Computational Science Initiative. My research is focused on machine learning and signal processing theories, models, and algorithms for various scientific applications, primarily bioinformatics and computational biology.

A new named postdoctoral fellowship position in Applied Mathematics and Scientific Computing is available at Brookhaven National Lab (BNL)

The Applied Mathematics Group of the Computational Science Initiative (CSI) at Brookhaven National Laboratory (BNL) invites exceptional candidates to apply for the Amalie Emmy Noether Fellowship in applied mathematics and scientific computing.

This fellowship offers a unique opportunity to conduct research in a broad set of fields, including reduced order modeling, uncertainty quantification and scalable computational statistics for Bayesian inference, optimization and control for decision making under uncertainty, scientific machine learning, high-dimensional inverse problems, multiscale modeling, integrated computational modeling frameworks, data science for streaming or “in-situ” (within simulation) analytics in high performance computing (HPC), and numerical methods. The methods and fundamental advances made in the course of this research will further the progress of applications of interest to BNL and the Department of Energy (DOE). Examples of such applications might include: data-driven uncertainty quantification and hybrid process-based/data-driven modeling for climate prediction and resilience planning, optimal experimental and simulation design for drug discovery and materials science, and large-scale data processing for particle accelerator experiments. The followship includes access to world-class HPC resources, such as the BNL Institutional Cluster and DOE leadership computing facilities. Access to these platforms will allow computing at scale and will ensure that the successful candidate will have the necessary resources to solve challenging DOE problems of interest.

This program provides full support for a period of two years at CSI. Candidates must have received a doctorate (Ph.D.) in applied mathematics or a related field (e.g., mathematics, physics, engineering, statistics, operations research, or computer science) within the past five years. This fellowship presents a unique chance to conduct interdisciplinary collaborative research in BNL programs with a strongly competitive salary. Recipients will be allowed to select a direct mentor from a list of CSI staff scientists. This mentor will help the recipient define and pursue their own research agenda during their appointment.

For more information, visit:

Apply for 2021 NSF Math Sciences Graduate Internship (MSGI)

We are happy to announce the opportunity to apply for 2021 NSF Math Sciences Graduate Internship (MSGI) to work on the research project entitled: Uncertainty-Aware Data-Driven Models for Optimal Learning and Robust Decision Making Under Uncertainty. (Mentors: Drs. Nathan Urban & Byung-Jun Yoon)

This project aims to develop Scientific ML techniques that enable objective-driven uncertainty quantification (UQ) for data-driven models. We will focus on developing theories and algorithms that can ultimately lead to an automated learning procedure of effective surrogates for complex systems that can be used for making optimal decisions robust to system uncertainties and surrogate approximation errors. These goals will be attained based on a Bayesian ML paradigm, in which we integrate scientific prior knowledge on the system and the available data to obtain a prior directly characterizing the scientific uncertainty in the physical system, quantify the uncertainty relative to the objective, develop optimal operators robust to the uncertainty, and design strategies that can optimally reduce the uncertainty and thereby directly contribute to the attainment of the objective. Potential applications of this methodology will be discussed with the student, but may focus on biological and biomedical discovery science. Detailed information of this project can be found in the project catalog at the following link (search for reference code: BNL-URBAN1):

The NSF Mathematical Sciences Graduate Internship (MSGI) program is aimed at students who are interested in understanding the application of advanced mathematical and statistical techniques to “real world” problems, regardless of whether you plan to pursue an academic or nonacademic career. Internship activities will vary based on the assigned research project and hosting facility. As part of your application, you will identify your top 3 research projects from the 2021 NSF MSGI Project Catalog:

Further information about the NSF Mathematical Sciences Graduate Internship program can be found at:

Application Deadline: January 13, 2021 4PM Eastern Time Zone

A new website launched for objective uncertainty quantification

Drs. Byung-Jun and Xiaoning Qian have jointly launched a new website, which aims to provide a convenient centralized access point to the latest research findings and developments relevant to objective-based uncertainty quantification (UQ) and optimal experimental design (OED).

This new website will provide a comprehensive list of research papers, software, resources, as well as the latest news and developments relevant to objective UQ. Main topics of interest that will be primarily featured on this new website include:

  • Mean objective cost of uncertainty (MOCU)
  • Optimal experimental design (OED)
  • Robust operator design for operations such as: classification, filtering, compression, control, and clustering
  • Optimal Bayesian Transfer Learning (OBTL)
  • Maximal knowledge-driven information priors (MKDIP)
  • Diverse scientific applications of MOCU and MOCU-based OED

Please visit for further information.


BioMLSP lab has openings for MS/PhD students

The BioMLSP lab is actively looking for 1~2 MS students and 1~2 PhD students who are strongly motivated to work on emerging research topics that involve machine learning & signal processing with applications in life science and materials science.

Potential applicants should contact Prof. Byung-Jun Yoon via email (bjyoon at ece dot tamu dot edu), which should include: (1) a brief description of the applicant’s general research interests and career goals, (2) CV, (3) undergraduate/graduate transcripts.




CNB-MAC 2019 will be held in Niagara Falls, NY, on September 7, 2019

The Sixth International Workshop on Computational Network Biology: Modeling, Analysis, and Control (CNB-MAC 2019) will be held in Niagara Falls, NY, on September 7, 2019. As in previous years, the upcoming CNB-MAC workshop will be organized in conjunction with the 10th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (ACM-BCB 2019), the flagship conference of the ACM SIGBio.

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CNB-MAC 2018 will be held in Washington D.C. on August 29, 2018

The Fifth International Workshop on Computational Network Biology: Modeling, Analysis, and Control (CNB-MAC 2018) will be held in Washington, D.C., on August 29, 2018. As in previous years, the workshop will be organized in conjunction with the 9th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (ACM-BCB 2018), the flagship conference of the ACM SIGBio.

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Tutorial at ISCAS 2017

Dr. Byung-Jun Yoon and Dr. Sung Il Park will jointly give a tutorial at the 50th IEEE International Symposium of Circuits and Systems (ISCAS 2017). ISCAS is the world’s premier networking and exchange forum for leading researchers in the highly active fields of theory, design and implementation of circuits and systems. This meeting will focus on the connection from Dreams to Innovation, with the aim of cultivating creative research-driven Ideas in Circuits and Systems as they transition to Innovations and fuel economic development. ISCAS 2017 will be held in Baltimore, MD, May 28-31, 2017.

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Tutorial on Models and Algorithms for Analysis of Large-Scale Biological Networks at EMBC 2017

Dr. Yoon will give a half-day tutorial on “Models and Algorithms for Analysis of Large-Scale Biological Networks” at the 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2017). EMBC 2017 will be held at the  International Convention Center (ICC) in Jeju Island, Korea, from July 11 to July 15, 2017.

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Dr. Yoon to give a keynote speech at SGTDP 2017

Dr. Yoon has been invited to give a keynote speech at the 3rd International Conference on Smart Grid Technology and Data Processing (SGTDP 2017).

SGTDP serves as a premier forum and aims to bring together researchers and experts from the external and internal, domestic and oversea academic institutes to exchange original ideas, discuss innovative designs, address important problems and share unique experiences on the field of the smart grid and data processing. SGTDP 2017 is organized by the Centre for Smart Grid and Information Convergence (CeSGIC) at the Xi’an Jiaotong-Liverpool University and it will be held in Suzhou, China, February 16 – 17 2017.

For more information about the conference, please visit:

CNB-MAC 2016 will be held in Seattle, WA

The 3rd International Workshop on Computational Network Biology: Modeling, Analysis, and Control (CNB-MAC 2016) will be held in Seattle, WA, on October 2, 2016. As in previous years, the workshop will be organized in conjunction with the ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (ACM-BCB), the flagship conference of the ACM SIGBio.

For more information about the CNB-MAC 2016, please visit:

Further information about ACM-BCB 2016 can be found at: